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SF Bay Area
Healthcare
Twist Bioscience
270
Employees
May 5, 2023
August 28, 2024

Twist Bioscience Layoffs: What Happened & Why?

In May 2023, Twist Bioscience, a leading synthetic biology and genomics company, announced a significant workforce reduction. Approximately 270 employees, or 25% of its workforce, were laid off as part of strategic actions to accelerate profitability. This article will delve into what happened, why it occurred, and the potential future impact of these layoffs.

Why did Twist Bioscience have layoffs?

The layoffs at Twist Bioscience were driven by a combination of economic pressures and internal restructurings. Despite achieving record revenue and increased orders, the company faced the need to accelerate its path to profitability. This led to the difficult decision to reduce the workforce by approximately 270 employees, or 25% of its total staff. According to CEO Emily M. Leproust, Ph.D., these actions are part of a broader strategy to focus on key commercial and development opportunities while transitioning manufacturing to the Factory of the Future to reduce costs. This move aligns with broader industry trends towards operational efficiency and financial prudence, especially in the biotech sector, which remains resilient amid economic uncertainties. The layoffs are intended to set Twist Bioscience up for long-term success, ensuring the company can continue to support its high-growth focus areas and serve its customers effectively.

Financial Impact and Future Directions

Twist Bioscience's recent layoffs are expected to yield significant financial benefits. The company anticipates separation costs between $9 million and $11 million, but these are offset by reduced operating expenses. In the short term, operating losses are projected to decrease, with year-end cash expected to rise to $320 million. Long-term, Twist aims for adjusted EBITDA breakeven by fiscal 2024, with a projected year-end cash of $220 million.

Strategically, Twist is transitioning manufacturing to its Factory of the Future to cut fixed costs and streamline operations. The company is focusing on high-growth areas like Next-Generation Sequencing and Biopharma Solutions, launching new products and partnerships to drive future success.

Impact on Industry

The layoffs at Twist Bioscience are likely to have a ripple effect across the healthcare industry. As the company reduces its workforce by 25%, other biotech firms may follow suit, prioritizing profitability and operational efficiency. This trend could lead to a leaner, more cost-effective industry, but it may also slow innovation and development in the short term. The focus on high-growth areas like Next-Generation Sequencing and Biopharma Solutions suggests that while some sectors may contract, others could see increased investment and activity, potentially reshaping the landscape of healthcare innovation.

Conclusion

Twist Bioscience laid off 270 employees to accelerate profitability, focusing on key growth areas and reducing costs. This move aims to achieve financial stability by 2024. The layoffs may prompt other biotech firms to prioritize efficiency, potentially slowing short-term innovation but boosting long-term industry health. Twist's focus on Next-Generation Sequencing and Biopharma Solutions could reshape healthcare innovation. Future implications might include further strategic shifts to maintain competitive advantage.